“Our ability to recognize which hemorrhages are likely to expand and the quantifiable and measureable variables involved in expansion – cause, size, location, drainage, time since onset of symptoms – can help us select the appropriate patients for aggressive treatment to limit expansion and it can inform further therapeutic studies,” Dr. Caplan said.
Dr. Boulouis said his group’s results need to be replicated in an independent cohort, and that CT hypodensities may eventually serve as a simple widely used tool to help doctors manage patients according to their risk of hematoma expansion.
“It is still unclear what the CT hypodensities represent. They may be the direct or indirect marker of ongoing bleeding or a marker of hemorrhage ‘immaturity,'” he added.
Two of his coauthors have grants from the National Institutes of Health. Dr. Boulouis is funded in part by a J. William Fulbright Scholarship and a Monahan Foundation Biomedical Research Grant.
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