6. Search for underlying cause or source of bleeding with imaging
Chest x-ray can localize the side of bleeding in patients with massive hemoptysis in approximately 50 percent of patients and suggest an etiology in about 33 percent. However, the sensitivity is poor with up to 50 percent of patients with normal chest x-ray having positive findings on CT.21 CT should be obtained in high-risk patients even with mild hemoptysis, and all patients with moderate to severe bleeding, even if the chest x-ray is unremarkable. The diagnostic yield of CT is superior to that of bronchoscopy while the yield in localizing the lesion is comparable at 75 percent.7 CT is generally recommended prior to bronchoscopy for this reason. The mnemonic BATTLECAMP may be used to recall the important causes of hemoptysis: Bronchiectasis, Aspergilloma/AV malformation, Tuberculosis, Tracheo-innominate fistula, Lung cancer or abscess, Pulmonary embolism, Cocaine/Coagulopathy/Catemenial/Cystic Fibrosis, Autoimmune (vasculitis, systemic lupus erythematosus), Alveolar hemorrhage, Mitral stenosis, Pneumonia.
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ACEP Now: Vol 42 – No 11 – November 20237. Arrange for definitive management
Depending on the underlying cause, definitive management may include bronchial artery embolization, a bronchial blocker, surgical resection, or even heparinization or embolectomy in the case of pulmonary embolism. So next time you are faced with a patient with massive hemoptysis heading for respiratory failure in your ED, take an organized approach such as this seven-step one to maximize your patient’s chance of survival with good neurologic outcome.
A special thanks to Drs. Bourke Tillmann and Scott Weingart for their expertise on the EM Cases podcast that inspired this column.
Dr. Helman is an emergency physician at North York General Hospital in Toronto. He is an assistant professor at the University of Toronto, division of emergency medicine, and the education innovation lead at the Schwartz/Reisman Emergency Medicine Institute. He is the founder and host of Emergency Medicine Cases podcast and website.
References
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- Atchinson PRA, Hatton CJ, Roginski MA, et al. The emergency department evaluation and management of massive hemoptysis. Am J Emerg Med. 2021;50:148-155.
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- Li H, Ding X, Zhai S, et al. A retrospective study on the management of massive hemoptysis by bronchial artery embolization: risk factors associated with recurrence of hemoptysis. BMC Pulm Med. 2023;23(1):87.
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- Fekri MS, Hashemi-Bajgani SM, Shafahi A, et al. Comparing adrenaline with tranexamic acid to control acute endobronchial bleeding: A randomized controlled trial. Iran J Med Sci. 2017;42(2):129-135.
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- Hankerson MJ, Raffetto B, Mallon WK, et al. Nebulized tranexamic acid as a noninvasive therapy for cancer-related hemoptysis. J Palliat Med. 2015;18(12):1060-2.
- Gopinath B, Mishra PR, Aggarwal P, et al. Nebulized vs IV tranexamic acid for hemoptysis: a pilot randomized controlled trial. Chest. 2023;163(5):1176-1184.
- Tomaselli GF, Mahaffey KW, Cuker A, et al. 2020 ACC expert consensus decision pathway on management of bleeding in patients on oral anticoagulants: A report of the American College of Cardiology solution set oversight committee. J Am Coll Cardiol. 2020;76(5):594-622.
- Santoshi RK, Patel R, Patel NS, et al. A comprehensive review of thrombocytopenia with a spotlight on intensive care patients. Cureus. 2022;14(8):e27718.
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