Patients in the immediate and delayed angiography groups showed similar rates of the secondary endpoints such as survival until hospital discharge, neurologic status at ICU discharge, myocardial injury, need for renal-replacement therapy or duration of mechanical ventilation.
However, immediate angiography significantly delayed median time to target temperature. It was 5.4 hours in the immediate group and 4.7 hours in the delayed group, a 19 percent increase.
“We’re not sure how serious that is,” said Dr. Lemke, “but it’s something to consider.”
While 62.9 percent of patients in the immediate angiography group survived with good cerebral performance, mild disability or moderate disability, the rate was 64.4 percent in the delayed group, a non-significant difference.
The study was done at 19 medical centers in the Netherlands.
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