Summary
Multiple probiotics have been shown to shorten the duration of watery diarrhea by about 24 hours and have demonstrated the ability to decrease the number of diarrheal stools even earlier in the course. The most commonly studied beneficial probiotic is LGG, and other beneficial strains include Lactobacillus reuteri and Saccharomyces boulardii. For families of children with acute infectious watery diarrhea, probiotics should be routinely discussed as a potential means of symptom improvement.
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ACEP Now: Vol 38 – No 01 – January 2019Dr. Jones is assistant professor of pediatric emergency medicine at the University of Kentucky in Lexington.
Dr. Cantor is professor of emergency medicine and pediatrics, director of the pediatric emergency department, and medical director of the Central New York Regional Poison Control Center at Upstate Medical University in Syracuse, New York.
References
- Allen SJ, Martinez EG, Gregorio GV, et al. Probiotics for treating acute infectious diarrhoea. Cochrane Database Syst Rev. 2010;(11):CD003048.
- Szajewska H, Skórka A, Ruszczynski M, et al. Meta-analysis: Lactobacillus GG for treating acute gastroenteritis in children—updated analysis of randomised controlled trials. Aliment Pharmacol Ther. 2013;38(5):467-476.
- Dinleyici ED, Dalgic N, Guven S, et al. Lactobacillus reuteri DSM 17938 shortens acute infectious diarrhea in a pediatric outpatient setting. J Pediatr (Rio J). 2015;91(4):392-396.
- Dinleyici ED, PROBAGE Study Group, Vanderplas Y. Lactobacillus reuteri DSM 17938 effectively reduces the duration of acute diarrhoea in hospitalised children. Acta Paediatr. 2014;103(7):e300-305.
- Hong Chau TT, Minh Chau NN, Hoange Le NT, et al. Double-blind, randomized, placebo-controlled trial of Lactobacillus acidophilus for the treatment of acute watery diarrhea in Vietnamese children. Pediatr Infect Dis J. 2018;37(1):35-42.
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