The biggest pseudo-surprise (we were not remotely surprised to learn) was that the “honor” for the class of drug most likely to cause a false positive on a urine drug toxicology test goes to tricyclic antidepressants (TCAs). TCAs can cause false-positive readings for five different drugs: PCP, LSD, amphetamines, opiates, and methadone. The runners-up for medications causing the most false positives on the urine toxicology test were ibuprofen and first-generation antihistamine medications such as diphenhydramine, hydroxyzine, and promethazine.
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ACEP Now: Vol 35 – No 07 – July 2016Tune in for the next episodes, which will look at unusual seizures (ie, the ones that don’t respond to benzodiazepines).
Dr. Faust is a senior emergency-medicine resident at Mount Sinai Hospital in New York. He tweets about #FOAMed and classical music @jeremyfaust.
Dr. Westafer is chief resident at the Baystate Medical Center at Tufts University in Springfield, Massachusetts. Follow her @LWestafer.
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