The Case
A 49-year-old man presents to the emergency department with an acute onset of back pain. He was carrying some heavy groceries and felt something pull in his lower back. He took some naproxen, which he uses as needed for an old high school football injury, but is still in pain. You do not find any red flags on the history and physical examination. He is feeling better after a dose of morphine, but he still has difficulty bending and walking. It’s time to consider what medications to discharge him home with.
Explore This Issue
ACEP Now: Vol 36 – No 05 – May 2017Background
There are about 2.7 million visits to the emergency department annually for low back pain. While the vast majority of visits are due to benign conditions, this diagnosis can be frustrating for patients and physicians.
One thing physicians have to consider is not missing the uncommon but dangerous conditions like spinal epidural abscess, osteomyelitis, cauda equina syndrome, and pathological fractures. Multiple red flag lists have been published to help physicians identify patients at risk for some of these serious conditions (eg, TUNA FISH, see Table 1). While no list is complete, they can be helpful.
Patient demands for imaging can be another source of frustration. The ACEP Choosing Wisely recommendation encourages physicians to avoid lumbar spine imaging:
Avoid lumbar spine imaging in the emergency department for adults with non-traumatic back pain unless the patient has severe or progressive neurologic deficits or is suspected of having a serious underlying condition (such as vertebral infection, cauda equina syndrome, or cancer with bony metastasis).
An additional frustration is the lack of efficacious treatments for low back pain. Acetaminophen has been shown not to affect recovery time compared to placebo.1 Adding cyclobenzaprine or oxycodone/acetaminophen to naproxen alone was shown not to improve functional outcomes.2
There are also concerns about the appropriate use of opioids. ACEP has a clinical policy on prescribing opioids and specifically addresses ED patients with acute low back pain.3 It gives three Level C recommendations:
For the patient being discharged from the emergency department with acute low back pain, the emergency physician should ascertain whether nonopioid analgesics and nonpharmacologic therapies will be adequate for initial pain management.
Given a lack of demonstrated evidence of superior efficacy of either opioid or nonopioid analgesics and the individual and community risks associated with opioid use, misuse, and abuse, opioids should be reserved for more severe pain or pain refractory to other analgesics rather than routinely prescribed.
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One Response to “Naproxen, Diazepam Evaluated for Treating Acute, Nontraumatic Low Back Pain”
June 30, 2017
jeff wuBefore we remove another medication from our already anemic quiver in the treatment of back pain, I think we have to be more realistic of the goals of the community ED doc. The conclusion of the authors may be correct based on the parameters of the study, but I disagree with their primary end point, and its application to the actual practice of what we do everyday in the ED.
The study focuses on a change in functional outcome at 1 week and 3 months. I don’t know a single practitioner who believes that any treatment we render for back pain in the ED is improving their long-term outcome. Let’s be honest, we just want them to feel a little better right now. What I would like to see is a study to evaluate the change in pain shortly after taking diazepam. If all we cared about was functional outcome at 1 week and 3 months, we should stop prescribing pain medication for fractures, kidney stones, and other painful conditions–at least until a study shows improvement of long-term functional outcome by treating the associated pain with those ailments.
By the way, Anand notes in his blog that the study had a low inclusion rate and did not control for unemployment rate. Perhaps a better powered study that controlled for those types of variables, and gave us a more meaningful end-point would convince guys like me to change my practice.