Dr. Miguel O’Ryan from the University of Chile in Santiago recently reviewed persistent and transient H. pylori infections in childhood. He told Reuters Health by email, “In regions similar to Chile, infection with H. pylori that will persist over time will most probably be acquired within the first three years of life. The great majority of these children will not develop symptoms within the following three to five years. It remains to be seen how many will develop any disease later in life.”
“Our data suggests that if H. pylori persistence is the main trigger for diseases later in life (cancer or ulcer or both) in a subset of individuals, vaccination to avoid infection (similar to the papilloma virus approach) would have to occur before two years of age,” Dr. O’Ryan said.
“At the moment, information available does not suggest that these children should be treated but this may change for subsets of children, if we can identify early markers for future disease,” he concluded.
Chongqing Kangwei Biological Technology funded the trial and employed one of the 22 authors.
Dr. Zou did not respond to a request for comments.
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